Tumor Evolution & Progression

Fund Technology Advancements for Immagin NuclearEnzyme Activity

I feel funding advancements for "In-Cell" Imaging would be wise. For example, a lot information into tumorigenesis may be obtained if we were able to differentially image Histone acetylases/deacetylase activity within intact tissue.

What is the research problem

There is a literature gap with regard to epigenetic regulation of acetylases. The significance of certain studies which use dominant negative mutant proteins can be more fully appreciated in light of quantitating spatial enzyme activity.

What is your proposed solution

Provide funding for the above stated innovations.


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Idea No. 59