Web-based resources are available offering information on pre-clinical, clinical, genomic and theoretical aspects of cancer, including not only the comprehensive cancer projects such as the International Cancer Consortium (ICGC) or the Cancer Genome Atlas (TCGA), but also less-known and more specialized projects on pediatric diseases such as the Pediatric Cancer Genome Project (PCGP). However, in case of data on childhood cancer there is very little information that is publicly available. Several web-based resources and tools offer general biomedical data which are not purpose-built, for neither pediatric nor cancer analysis. Additionally, many web resources on cancer focus on incidence data and statistical social characteristics as well as self-regulating communities. Knowledge of both, germline as well as somatic mutations in pediatric cancer patients is crucial for the development of novel therapeutics, and personalized medicine-based predisposition. Data integration and management linked to existing childhood cancer Web resources can help to identify not only the existing resource, but also those that are missing.