Tumor Evolution & Progression

Modulation of mitochondria for prevention of cancer

Mitochondria is central to cancer progression & several drugs don't act on cancer cells with bad quality mitochondria. It has been reported that Cancer cell phenotype can be reversed by replacing mitochondria.

What is the research problem

Since mitochondria play a central role in cancer progression, correcting mitochondrial genome may prove to be beneficial tool for cancer treatment

How will your solution make a difference

The cancer cells will no longer be supported by the internal metabolic system. It will also help us tackle a major problem of drug effectiveness in cancer cells.

What is your proposed solution

Using CRISPER based tools or the mitochondrial replacement tools, the cancer phenotype may be altered.

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Idea No. 110