Environment, lifestyle, behaviors and PROs inform response to, and adherence with, precision medicines and should be standard reporting in clinical trials.
Expanding Clinical Trials
Cancer Research Ideas - Expanding Clinical Trials (Archived)
Cancer clinical trials continue to be the gold standard by which new preventive, treatment, supportive care, and other interventions are tested and compared with existing interventions. New clinical trial designs are emerging with the recognition that a single cancer type may consist of many different molecular subtypes and that a given molecular alteration may drive many different types of cancer. At the same time, it is important that more patients have the opportunity to enroll in trials, to ensure that the results of trials are as broadly applicable as possible and that answers are obtained as quickly as possible.
The submission period for Expanding Clinical Trial ideas ended on July 1. However, we encourage you to sign up for regular e-mail updates about the National Cancer Moonshot Initiative at the Cancer Moonshot Milestones web page.
More people would enter clinical trials if they were guaranteed to receive the actual drug instead of a placebo.
I would donate my intellectual property on this invention to the Moonshoot Initiative, if this approached is pursued and demonstrated to be effective in the treatment of cancer, as I have demonstrated in my own clinical trials.
Patients don't have an easy way to determine which cancer trials they are eligible for. We've built an automated system where a patient can chat with our AI about their treatments and see options they are likely to qualify for and we help them apply
Too many general oncologists are unaware of the explosion of new drugs and trials for lung cancer.
If they had up to date information they might refer more patients for trials. Many patients are unaware that their oncologists are out of date.
I have metastatic pheo and was the patient rep on a clinical trial here in the UK. The trial closed for lack of numbers despite the eligibility criteria being changed not long before the trial closed. Everyone involved was very disappointed.
In order to attract patients, forced randomization has to change. We need newer faster trial designs. RTC is not the only way to arrive at truth. If biostatisticians are so obdurate that they can't fathom a different approach, please fire them.
launch large research program to investigate phytocannabinoid-based preparation as antitumor agents.
rationale for this has been summarized by NCI here: http://www.cancer.gov/about-cancer/treatment/cam/hp/cannabis-pdq
There is no standardized treatment modality for potentially resectable pancreatic cancer. Treatment strategies for potentially resectable patients of pancreatic cancer consist of surgery first or chemotherapy first.
Basket and umbrella trials within the National Clinical Trials Network (NCTN) bear huge administrative burden in building genomic screening for each endeavor; this becomes inefficient very quickly. One screening platform should be built for the NCTN.
Nutritional cures for Liver Cancer include the following:- Frankincense oil shrinks tumors, while
Cannabis oil reduces Biliary cancer to a great extent.
Cancer patients are unable to participate in Phase I or II Clinical Trials because the trials are conducted at Cancer Centers far away from the patients' place of residence. Ask leading cancer centers to work with smaller institutions across the USA.
A US/EU/Chinese patent issued, CE marked therapeutic device for tissue engineering, uses safe radio-frequencies in the presence of an instantaneous magnetic field to target any solid tumor- sparing normal tissue - to effectively treat and palliate.
Patients diagnosed with locally advanced NSCLC have a poor prognosis with 5-year survivals of 15-20% after chemoradiotherapy. RT dose escalation may improve survival and local control but new innovative approaches are needed