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  • Precision Prevention & Early Detection
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      Precision Prevention & Early Detection
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      Submitted by Physician (@swedish.physician) kudos icon + 01/Jul/16 10:53 PM

      Precision Prevention & Early Detection

      Does chemicals in blood correlate to cancer?

      Does chemichals measured in blood correlate to different types of cancers? It would be interesting to examine.

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      Submitted by Physician (@swedish.physician) kudos icon + 01/Jul/16 10:39 PM

      Precision Prevention & Early Detection

      Liverspecific Ferritin could help find livermetastasis early

      Ferritin measured in the blood has two origins. If the ferritin that leaks out from the liver was measured specifically the chances of detecting livercancer/metastasis or hepatocellurdeath would increase compared to only measuring Serum-Ferritin.

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      Submitted by David Hicks (@david.hicks) kudos icon + 01/Jul/16 9:43 PM

      Precision Prevention & Early Detection

      Early detection is dependent on knowing the genesis of cancer.

      Cancer starts with a stalled, or the failure to start, G1 phase of the cell cycle. There are many reasons why this process becomes stalled. Familial cancers fail to start the G1 phase because a mutation prevents it. Adult cancers are stalled G1 phase

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      Submitted by Physician (@swedish.physician) kudos icon + 01/Jul/16 9:32 PM

      Precision Prevention & Early Detection

      Examine exhaled volatile organic compounds as markers of cancer

      By analyzing exhaled volatile organic compounds biomarkers of cancer can be identified. Different patterns of biomarkers could be identified between different groups of patients. The procedure is not invasive and could be used to find lungcancer.

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      Submitted by carla (@carla0) kudos icon + 01/Jul/16 9:30 PM

      Precision Prevention & Early Detection

      Liver cancer early detection using cloud computing and AI

      We propose building an AI application to automate and standardize the screening of patients at high risk of developing liver cancer with the goal of making screening highly accessible and thus finding liver cancer before it is symptomatic

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      Submitted by Phil Stashenko (@pstashenko) kudos icon + 01/Jul/16 9:03 PM

      Precision Prevention & Early Detection

      Dysbiotic oral microbiomes increase cancer risk and recurrence

      Despite advances against other cancers, oral cancer mortality has not improved in 4 decades. Our findings indicate that the oral microbiome increases cancer risk when it is dysregulated, which offers new diagnostic biomarkers and therapeutic targets.

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      Submitted by Drisha Leggitt (@drishaleggitt) kudos icon + 01/Jul/16 6:56 PM

      Precision Prevention & Early Detection

      Catch 16 Cancers at Earliest Stages: "Blood Biopsies" & CDA Tech

      Reinvent screening/early detection by analyzing simple blood tests using multi-level/parameter algorithm & Cancer Differentiation Analysis tech; 30,000 cases confirm CDA identifies16 different cancer types/locations-often before cells form tumors.

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      Submitted by Katherine Baird (@katherinebaird) kudos icon + 01/Jul/16 6:30 PM

      Precision Prevention & Early Detection

      Rethinking the Role of Chemicals in Precision Prevention

      Recent research in toxicology, epidemiology and cancer biology strongly indicates that toxic industrial chemicals and pollutants are having a significantly greater impact on the incidence of cancer than previously thought.

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      Submitted by Physician (@swedish.physician) kudos icon + 01/Jul/16 6:28 PM

      Precision Prevention & Early Detection

      Screen for change in tumor markers to diagnose cancer early

      Analyze tumor markers in young healthy adults. Repeat testing these individuals when they are middle age and old to dectect significant change in the tumor markers which indicates the need for further examination of the patient to exclude cancer.

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      Submitted by liu.hongfang kudos icon + 01/Jul/16 6:02 PM

      Precision Prevention & Early Detection

      Individual knowledge delivery for cancer surveillance

      With the widespread adoption of Electronic Health Records (EHRs), it is now possible to implement clinical decision support (CDS) tools in practice to deliver cancer screening recommendations leveraging individual patient medical information.

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      Submitted by jweidhaas (@jweidhaas) kudos icon + 01/Jul/16 5:59 PM

      Precision Prevention & Early Detection

      New MicroRNA based biomarkers of cancer risk

      There are new RNA based genetic differences in people that are strong biomarkers of cancer risk, and need additional study in appropriate clinical trials. Such mutations can be modified by lifestyle, and afford a true opportunity for prevention.

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      Submitted by Tracy Crane (@tecrane) kudos icon + 01/Jul/16 5:53 PM

      Precision Prevention & Early Detection

      Prevention of Cancer Using Multi-modal Lifestyle Behavior Health

      Evidence is mounting for adherence to a healthy lifestyle to reduce cancer risk. A healthy lifestyle pattern defined by tobacco use, alcohol intake, BMI, diet quality & physical activity may reduce risk for incident cancer & mortality. CA Thomson

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      Submitted by mspencer (@mspencer) kudos icon + 01/Jul/16 5:50 PM

      Precision Prevention & Early Detection

      Academy for Radiology Research

      ARR recommendation

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      Submitted by Gitanjali and Priyanka Multani (@multanitwins) kudos icon + 01/Jul/16 2:39 PM

      Precision Prevention & Early Detection

      B7-H4 Detection Within a Microfluidic System Via Sandwich ELISA

      Ovarian cancer is recognized for having a dismal prognosis largely because of the lack of an effective early-detection method. Engineering a mechanism that is cost-efficient, quick, and user-friendly is paramount in augmenting survival rates.

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      Submitted by Bernatd King MD (@bfk011) kudos icon + 01/Jul/16 1:55 PM

      Precision Prevention & Early Detection

      Accurate detection of high risk prostate cancer utilizing PET/MR

      Study comparing standard screening and staging techniques (Prostate biopsy) for the detection of prostate cancer to PET/MR in patients with elevated PSA. Accuracy and cost effectiveness would be compared between the two approaches.

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