The initiative will prioritize scientific and clinical research data needs for addressing the burden of cancer in children, adolescents, and young adults. We must determine which research questions should be answered.
Answer one or more of the following questions in your response:
- What research questions can be addressed through improved childhood cancer data sharing?
- What common data would be needed to answer those questions?
Incidence of several cancers continues to increase in children and adolescents. Individual studies and international collaborations have made progresses in understanding risk factors of certain childhood cancers, yet gaps remain. The CCDI should also invest in supporting data sharing for etiologic research (population-based and mechanistic studies).
• Insights from epigenetics: In all hematologic malignancies, including acute and chronic leukemias, and lymphomas, there are both inherited and somatic genetic alterations that contribute to predisposition, transformation, and disease progression. While genomics plays a significant role in the onset and progression of such malignancies,... more »
- i would like to introduce you to my idea " relapse prediction using machine learning algorithms "
- my topic is about turning the initial data collected from the patients when introduced for first time before starting the treatment into insights using data science. it depends on each disease type and according to the treatment protocol.
- by using an Electronic Data Capture (EDC) system , we can turn... more »
I would like to write a new plan for two date sets for cancer therapy of youth.
One set of data is based on the pharmacological data set coming from the patient's cells embedded embryo of Zebrafish. Such PDX (Patient-Derived Xenograft Model; PDX) is now getting realistic and offer more precise medicine of cancer therapy.
Because of the mechanism of Zebrafish based PDX, each embryo of Zebrafish needs... more »
Cancer treatment outcomes depend on the hospital environment. Research should evaluate the effects of ambient lighting (color, intensity, timing), and the best time of day for chemotherapy and feeding and other interventions which can disrupt a patient's normal circadian rhythm. This initiative was chosen as representative of the recommendations from members of the Society for Research on Biological Rhythms (SRBR).
primary prevention of childhood cancers