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Design mobile app for handheld/tablet listing trials by disease, stage with quick summary as easy reference for
- eligibility, ineligibility criteria
- download protocol
- action link to share trial via email,
- geolocation for closest open site
Arachidonic acid is a key mediator of inflammation, which plays a role in carcinogenesis. Prostaglandins and leukotriene blockade may decrease the risk of premalignant transformation, influence cell survival and modify radiation response.
Many investigators do not follow CONSORT guidelines in publishing clinical trials. Incentivize complete reporting by linking adherence to CONSORT to subsequent grant application scoring.
Prospective Trial of Library Access to Research Articles for Patient +/- Caregiver During Hospitalization or Chemotherapy Infusions
Recent research estimates that patients and insurance companies pay $3B for unnecessary excess amounts of cancer drugs beyond what the patient needs. Pharmaceutical companies can personalize drug delivery and lessen financial toxicity for patients.
Clinical research doesn't always translate well into community oncology. We need to better understand differences between academic and community oncology to ensure maximal benefit to all cancer patients
New forms of communication bring both risks and benefits to cancer patients and professionals. The internet makes these scalable, amplifying the potential impact on cancer care. We need to study carefully whether social media helps or harms us.
Sodium butyrate (SB) is a generic drug used for ulcerative colitis to decrease inflammation. Some data suggest (SB) may also be a radiation sensitizer for cancer cells by inhibiting histone deacetylase (HDAC).
SEER, SEER-Medicare and other publicly accessible databases are not easy to find, access or analyze for non-researchers with novel ideas that could lead to breakthroughs. Reconfigure to make the databases hackable for the general public.
Autopsies provide essential information about the natural history of progressive cancer. The practice is on the decline because of the invasiveness.
Fund training for minimally invasive autopsy and how to make it less distressing for families
Well-designed, accessible predictive models can provide evidenced-based, personalized estimates of important clinical cancer outcomes. I recommend comprehensive development of nomograms to assist with shared decision making.