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The NIH/NCI have a reputation for funding "safe" research ideas - those with a high probability of success. The real breakthroughs in science come when we take big risks with the hope of big rewards. It is time.
In this exciting time of promise in cancer research, I suggest that we align the stakeholders in a collaborative effort to accelerate progress toward gentler treatments and cures for children. aPODD, a European non-profit, is an example of this.