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The immune system *almost* destroys cancers. Bone marrow transplants to force systemic host/graft have proven effective, but with obvious downsides. If we understood how NKLs decide to kill a little better, we could do a subtler version of this.
1) Sequence both healthy and cancerous tissue
2) Find consistent difference
3) Make CRISPR to insert cytotoxin at the difference
4) Deliver CRISPR into cells [hard]